Specification

Version: 1.0
Revision Date: 03/28/2016
000000023874
12/18
4,4'-Methylene
bis(phenylisocyanate)
in vivo (Rabbit): Read-across based on grouping of substances (category
approach), Key study
Carbon Black in vivo (Rabbit): Experimental result, Key study
1,3,5-Trimethylbenzene in vivo (Rabbit): Experimental result, Key study
Iron oxide in vivo (Rabbit): Experimental result, Weight of Evidence study
Serious Eye Damage/Eye Irritation
Product:
No data available.
Specified substance(s):
Heavy aromatic
naphtha
in vivo (Rabbit, 24 - 72 hrs): Not irritating
Aromatic petroleum
distillates
in vivo (Rabbit, 24 - 72 hrs): Not irritating
1,2,4-Trimethylbenzene in vivo (Rabbit, 30 min): Not irritating
4,4'-Methylene
bis(phenylisocyanate)
in vivo (Rabbit, 24 - 72 hrs): Not irritating
Carbon Black in vivo (Rabbit, 24 - 72 hrs): Not irritating
Iron oxide in vivo (Rabbit, 1 - 72 hrs): Not irritating
Respiratory or Skin Sensitization
Product:
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause sensitization by inhalation.
Carcinogenicity
Product:
No data available.
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans:
Carbon Black Overall evaluation: Possibly carcinogenic to humans.
Crystalline Silica
(Quartz)/ Silica
Sand
Overall evaluation: Carcinogenic to humans.
US. National Toxicology Program (NTP) Report on Carcinogens:
Crystalline Silica
(Quartz)/ Silica
Sand
Known To Be Human Carcinogen.