Specification

Version: 1.0
Revision Date: 03/28/2016
000000023904
12/19
Heavy aromatic
naphtha
in vivo (Rabbit): Experimental result, Key study
Aromatic petroleum
distillates
in vivo (Rabbit): Experimental result, Key study
1,2,4-Trimethylbenzene in vivo (Rabbit): Read-across from supporting substance (structural
analogue or surrogate), Key study
4,4'-Methylene
bis(phenylisocyanate)
in vivo (Rabbit): Read-across based on grouping of substances (category
approach), Key study
1,3,5-Trimethylbenzene in vivo (Rabbit): Experimental result, Key study
Aluminum oxide in vivo (Rabbit): Experimental result, Key study
Serious Eye Damage/Eye Irritation
Product:
No data available.
Specified substance(s):
Titanium dioxide in vivo (Rabbit, 24 hrs): Not irritating
Heavy aromatic
naphtha
in vivo (Rabbit, 24 - 72 hrs): Not irritating
Aromatic petroleum
distillates
in vivo (Rabbit, 24 - 72 hrs): Not irritating
1,2,4-Trimethylbenzene in vivo (Rabbit, 30 min): Not irritating
4,4'-Methylene
bis(phenylisocyanate)
in vivo (Rabbit, 24 - 72 hrs): Not irritating
Aluminum oxide in vivo (Rabbit, 24 hrs): Not irritating
Respiratory or Skin Sensitization
Product:
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause sensitization by inhalation.
Carcinogenicity
Product: No data available.